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sweatbookHRRC Contributor Robert Lawson gives a straight up review on internet best-selling sweat cure "Stop Sweating & Start Living" by Mike Ramsey.

"Usually we stick to brick and mortar consumer products or prescription based medical treatments when reviewing courses of action for Hyperhidrosis - But with the rising popularity of all-natural treatments for the cure of excessive sweating, Mike Ramsey's "Stop Sweating and Start Living" has been making too much noise in the Hyperhidrosis market for us to ignore."

Read the full review here >>

Suffering From Sweaty Armpits?

Sweating, of course is a natural function of the human body - without it we would be very limited in our ability to effectively expel toxins and other waste from our bodies. Our primary sweat glands exist in our armpits, forehead, hands, groin and feet, and will normally be triggered through activities such as exercise, or in temperate climates.
Though for some, this 'normal' human function can persist to a point of abnormality, where effective treatment should be sought.

Chances are, if you are visiting this site, you may be experiencing these more abnormal symptoms of persistent underarm sweating, and very well could be suffering from a condition known medically as Axillary Hyperhidrosis...

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The Hyperhidrosis Research & Review Committee (HRRC) is an independent body of volunteer contributors worldwide with special interests in the ongoing research into Hyperhidrosis causes and treatments. The HRRC was founded as an independent collaborative to promote awareness and dissemination of information in the Hyperhidrosis specialty fields.

Our website provides information to consumers on the causes of excessive sweating, as well as regular reviews of consumer products and popular courses of treatment available to hyperhidrosis sufferers. If you are interested in becoming a collaborator on this and other hyperhidrosis specific websites, please contact us.

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Botulinum Toxin in the Treatment of Hyperhidrosis

Abstract(en) :

Excessive sweating may cause considerable disability, with psychological, social and occupational consequences. Primary hyperhidrosis may also play a key role in the pathogenesis of dyshidrotic dermatitis and some other skin diseases.

The aim of the present work was to evaluate a novel treatment of hyperhidrosis namely chemical sweat gland denervation with botulinum toxin type A (Btx A).

The effects of multiple intradermal injections of Btx A (total dose Botox® 0.5 U/cm2 on one occasion) were evaluated in palmar and axillary hyperhidrosis, using patients as their own controls. The abolition of sweating was objectified by comparing measured evaporation and the size of the sweating area assessed in iodine-starch tests between the treated and untreated side before and one week after unilateral injections. Hyperhidrosis disappeared or was highly reduced in 22 of 26 patients with an effect duration of 8-9 months in most patients.

Side-effects of palmar Btx A injections were restricted to a transient weakness of the hand muscles. This was studied by measurements of compound muscle action potentials of intrinsic muscles of the hand at supramaximal nerve stimulation and of muscle strength before and 3 weeks after treatment with Btx A and at a late follow-up after 15 – 37 weeks. Post-treatment values of these measures of intrinsic hand muscle function were significantly reduced at 3 weeks and had almost returned to normal at 37 weeks.

Sweat gland histology and immunoreactivity were studied in skin biopsy specimens taken before and 2.5 – 6 months post-treatment. The lumen of the secretory tubule was diminished, but no atrophy of sweat gland cells was seen. A tendency to reduced staining with the neuronal marker PGP 9.5 suggested sudomotor nerve degeneration. Immunoreactivity of the neurotransmitters VIP and CGRP was unchanged.

Patients with primary focal hyperhidrosis were found to have a marked reduction of life quality (increased Dermatology Life Quality Index score) – a reduction which, however, was almost reversed at measurement 5 months after treatment with Btx A.

Ten patients with vesicular hand dermatitis were treated unilateraly with Btx A. Seven out of ten displayed marked improvement in both objective and subjective ranking measures of the dermatitis.

In conclusion, focal hyperhidrosis and dyshidrotic hand dermatitis may be effectively treated with intradermal injections of botulinum toxin. Side-effects occur, but are minor and transient. The reduced sweat production is associated with minor changes in sweat gland histology and innervation. The considerably impaired quality of life demonstrated in patients with primary hyperhidrosis can be largely reversed by intradermal Btx A therapy.

More Information:

Uppsala University, Medicinska vetenskapsområdet, Faculty of Medicine, Department of Medical Sciences
Publication type:
Doctoral thesis, comprehensive summary (Other academic)
Language:
English
Place of publ.:
Uppsala
Publisher:
Acta Universitatis Upsaliensis
Pages:
67
Series:
Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine, ISSN 0282-7476; 1164
Year of publ.:
2002
URI:
urn:nbn:se:uu:diva-2105
Permanent link:
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-2105
ISBN:
91-554-5340-6
Subject category:
MEDICINE
Research subject:
Dermatology and Venerology